Since we've gone over a year without cable (or even antenna) TV, we have learned the guilty pleasure of renting (and in a few cases buying) shows we either miss out on, or just plain miss.
I can't say I've gotten into "Lost", but my wife and kids sure have. To me it's just a bunch of psychotic freaks stuck on an equally freaky island, but they like it, so hey, you might.
For me, I would suggest "Monk", "Lonesome Dove: The Series/Outlaw Years", I'll 2nd (0r is it 3rd) "Stargate SG-1", and you can NEVER go wrong with old episodes of "Night Court" and "Soap".
Share them with someone you love! ;~D