I had a similar problem this week. I had installed some updates and all javascript quit working on my system which made many things associated with IE no longer work. I ended up having to reinstall Microsofts Scripting engine.
http://support.microsoft.com/default.aspx?scid=kb;en-us;236846
http://msdn.microsoft.com/library/default.asp?url=/downloads/list/webdev.asp
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