Win10 version 1909, Groupy v1.32, and Sage 50 Pro Accounting, release 2017.2.
Groupy works well with all my applications, except Sage. After a short time working in Sage, opening and closing app windows and dialog boxes, Sage windows will briefly stop responding to mouse clicks (but not to window moves by dragging the title bar), then move some windows from one monitor to another (I have 3), and some, but not all, of the windows will maximize. No other application is affected when this occurs. After that happens control returns but I have to resize each affected window using the window restore button in the upper right and then reposition it. This behaviour is always preceded by a couple of seconds of Sage not responding in any of its non-modal windows.
This happens regularly and frequently until I turn Groupy off on its application window. Sage windows' size and location remain steady and respond as expected to mouse clicks. I have tested this just through daily Sage use. I didn't realize that Groupy was causing it until I turned it off in mid frustration 
I have set Groupy to never automatically group Sage windows. Sage is installed on a local drive but accesses NAS storage data (the same can be said of my Outlook 365 and Visual Studio 2019 installs which work flawlessly).
Is it just Sage?