I really like the idea of being able to switch layouts depending on my task at hand but as I have multiple monitors, I find managing them is a bit of a chore.
I've currently got my setup so that my 'everyday' icons are on my left monitor and my task specific ones on my right.
I have several clients I support and each client has their own Fence, all on the right screen but I'm now getting to the point where I don't have enough space for all my clients.
For that reason I'd like an option to have an option with 'Desktop Layouts' to independently switch a single monitor at a time. That way, I only need to create one desktop setup on my left monitor and have a separate desktop for each client on my right.