Here I thought it was me. I don't know what happened to mine either. I've been using CursorFX for a long time (6 months) and CursorXP prior to that for year.
One day, I went to change my cursor. I brought up the program, selected a new cursor and it sat at the loading/waiting screen FOREVER. I have the same system parameters as the original poster, and have tried the same things - Vista Ult 32 bit, Uninstalled and reinstalled many times, many ways.
First uninstall/reinstall was through Implule, second was through Windows, third uninstall was through TuneUp Utilities with reinstall through Impulse. All with reboots inbetween and even registry cleaner programs also to remove stray entries.
The only thing I can think of is that a cursor I downloaded recently is causing the hang-up. But I haven't tried to use that one yet.
Can anyone help resolve this?