After purchasing CursorFX Plus last night and installing it on Vista Ultimate, I've found my PC very sluggish. Toggling CursorFX with Ctrl+Shift+V shows that the cause is a combination of CursorFX CPU usage at around 5 to 10% and Tabtip.exe which rockets to 20 to 30%. Switching CursorFX off returns Tabtip.exe back to "0%". I do have a Wacom tablet so need to be running tabtip.exe.
Aside from this "killer" issue, CursorFX looks cool.