Kaspersky caused me no end of troubles with DX, so i ended up getting rid of it and using Avast. There was a lot of script blocking. Im sure there is a way to turn it off, i was able to turn it off.
As for the 2nd drive idea, i keep a CLONE of my laptop drive with me at all times.
I use TRUE IMAGE to clone. its great. When i reload the laptop i take the OLD drive and put it in the BAY drive holder, then the NEW drive in the internal slot.
Once the OS is loaded i can BOOT to either of these drives to see what i missed, or to get REG keys or Serial #'s i forgot. its a great way to check. Just wish i didnt load so much crap on the machine!