Running out of options for you here...
How much space does your hard drive have left?
Does an SFC scan find issues?
https://www.windowscentral.com/how-use-sfc-scannow-command-fix-problems-windows-10
Are you using OneDrive, and if so, are the local files actually pathed to it, for example, instead of:
C:\Users\YourUsername\Documents\My Games
The path reads something like:
C:\Users\YourUsername\OneDrive\Documents\My Games
Sean Drohan
Stardock Support Manager