In the "background pausing" section of Descapes 10's Advanced Settings, when I have "Pause when a window is maximized" & "Only pause monitors that match the above rule" selected it only applies to monitor 1 for me. But as for monitor 2 the background video still seems to continue playing even though a program is maximized on that monitor, I noticed this due to the help of the window being partially transparent.

I'm also using a DVI-(D)(I think) to hdmi adapter for monitor 2 if that helps