In my case I designed and built a home office suite of furniture that allows me to work at one of my computers while standing and the other while sitting. So, when the I start getting 'comfortably numb' I stand up and walk over to the other computer and work there for a while. When my legs start to get tired then it's back to the chair.
Oh, and I also go for walks and take the dog outside for her much beloved game of fetch. These regular activities help to reduce the signs of lividity in the old posterior.