It's taken me a while to notice the exact behavior of this bug, but it's keeping me from wanting to use OD as it makes the whole experience more frustrating.  I have not yet confirmed what causes this to happen, it seems random.  I'm currently using the free version of OD, though a friend of mine with the Plus version has confirmed the same thing on his computer.  Here's what happens when the bug occurs:

1. I have multiple programs open (using OD as the taskbar)

2. I'll click on another icon to switch focus to it (about 95-98% of the time this works no problem)

3. Instead of switching to it, absolutely nothing appears to happen.  The new program is not up and I'm still focusing on the old one.

4. If I click on the icon AGAIN, then I suddenly see an animation of the program I wanted already open, and minimizing, as though it were already up and I was clicking on it again to minimize it.

In other words, randomly (I'm guessing 2-5% of the time), my clicks act like they're not registering, but clearly something is if the program wants to minimize if I click on it again.  While this doesn't sound like often, using the computer heavily means this might occur a dozen or two times within the course of an hour, meaning OD simply isn't worth it to me if this can't get fixed.  This appears to happen to any program, but here are some that I've confirmed it with:

Wordpad

XYplorer

Adobe Premiere CS5 (64-bit)

Adobe Audition CS 5.5

I am running Windows 7 SP1 64-bit.