What's your OS? Which version of OD do you have? Does anyone else have access to your computer?
Your OD+ settings sould be stored here:
C:\Documents and Settings\{username}\Local Settings\Application Data\Stardock\ObjectDock(Plus)
Are they there? If not, rebuild your dock the way you want and then backup the settings from the folder...store them in a different
location as ODplusSettings.bak then restore when you need...