Yes, I guess I should have been more clear. It is a wired mouse, so definitely not a battery problem and it ONLY affects my desktop icons, nothing else. I can freely click as I usually do on my task bar, on object dock, in any program, it just takes one extra click to focus the desktop for some reason.
Also, this IS a problem with using object dock, as I've quit object dock and the problem stops instantly.
I'm mostly just curios to see if anyone else has witnessed this specifically related to their desktop and running object dock. If not, maybe I am a freak and have some setting wrong somewhere.