The quick answer is yes, but give it a try like voidcore suggested.  If you lose information on screen you might go in and change the dpi setting to see if that might help.  Your biggest problem will be the WindowBlinds configuration window.

yes and no

the skins should work, but you might run into things like taskbar too tall or you might get tempted to try an IRB skin and find out the start panel won't fit

you'll also have issues with WB config - it's coded for one size - doesn't resize and it won't fit at less than 768 - so you won't see the bottom parts