The Windows Vista Blog announced that Microsoft and Apple worked together to correct a problem with iPods on Vista, and an issue with the "Safely Remove Hardware" function. The download will be made available on Windows Update on May 22nd, but you can download the update now.
From the Windows Vista Blog....
"The long and short of it is this: Apple and Windows have partnered together to ensure a great experience in using Windows Vista with iTunes and the iPod, and both companies recommend you download this update."