I had installed vairous of those programs and I usually tweak around with them and look in awe at them for about an hour.........until my curiosity is satisfied and I forget at them.
A couple of months later I do my usual "throw out the programs I don't need anyway"-sweep and they dissappear from my HD.

I guess it depends what you are used to and how important little flashy tweaks are for you. I usually just get annoyed by them, very fast. Furthermore, I am soooo used to use my taskbar or ALT-TAB to switch between the windows, that I simply forget that there would be a flashier way to do it.
.....aahh, and Winplosion gave me a false-positive from Kasperksy (that was a while ago though, and I don't know wether Kaspersky fixed that).