I don't know if anybody has experienced any problems, so this would just be for information only.
I resently installed Flight Simulator 2004 and discovered that all the sliders didn't work, as I was trying to increase gfx settings. Then I saw a thread on nvidia's board saying that WB caused the problem. And true enough, when I unloaded WB, FS2004 work as it's supposed to.
But Splinter Cell 3 also crashed at startup, so I gave it a long shot and started the game with WB unloaded.. And it started right away.
So apparently there are some issues with WB and a few games.